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Projects

Current Projects

Host Genetic Control of the Microbiome

NIH R01 (2022-2026) | PI: William Cresko, Brendan Bohannan
Using experimental evolution and genome-wide association studies to understand how host genetics shapes microbiome composition and function.

Genomic Architecture of Parallel Evolution

NSF DEB (2023-2027) | PI: William Cresko
Investigating the repeatability of evolution by comparing genomic changes in multiple independently evolved stickleback populations.

META Center for Systems Biology

NIH (2017-2025) | Role: Co-Investigator
Part of the Microbial Ecology and Theory of Animals Center, studying host-microbiome interactions across multiple model systems.

Recent Completed Projects

Rapid Evolution Following Environmental Change

NSF (2013-2018) | Outcome: PNAS publication
Demonstrated evolution can occur within decades following the 1964 Alaska earthquake.

Syngnathid Genome Consortium

NSF & Moore Foundation (2014-2020) | Outcome: Multiple genome publications
Led sequencing and analysis of syngnathid fish genomes to understand unique trait evolution.

Methodological Developments

RAD-seq Technology

Years: 2008-present | Impact: 10,000+ users worldwide
Developed Restriction site Associated DNA sequencing for cost-effective genome-wide SNP discovery.

Stacks Software Pipeline

Years: 2010-present | Downloads: 50,000+
Created comprehensive software for building loci from short-read sequences.

Collaborative Networks

National & International: University of Alaska | Stanford Hopkins Marine Station | Max Planck Institute | Swedish Museum of Natural History

Campus Collaborations: Institute of Ecology and Evolution | Knight Campus | META Center | Genomics Core Facility

Data & Resources

All data available through: NCBI BioProject | Dryad | GitHub

For access to specific datasets or collaboration inquiries: wcresko@uoregon.edu

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