About

Learn about the Cresko Laboratory’s mission, history, and approach

Our Mission

The Cresko Laboratory advances our understanding of evolutionary processes through integrative genomic research. We seek to uncover the molecular mechanisms underlying adaptation, the dynamics of host-microbiome interactions, and the genomic basis of evolutionary change.

Our Approach

We believe that understanding evolution requires a multi-faceted approach:

  • Field Studies: We conduct long-term monitoring of natural populations across the Pacific Northwest
  • Laboratory Experiments: We use controlled experiments to test evolutionary hypotheses
  • Computational Biology: We develop and apply cutting-edge bioinformatic tools
  • Open Science: We share our data, code, and methods openly with the scientific community

Our History

The Cresko Laboratory was established in [year] when Bill Cresko joined the University of Oregon faculty. Since then, we have:

  • Published nearly 100 peer-reviewed papers
  • Developed RAD-seq technology, revolutionizing population genomics
  • Created Stacks, now used by over 5,000 researchers worldwide
  • Trained dozens of graduate students and postdocs
  • Secured continuous funding from NSF, NIH, and other agencies

Our Values

Excellence in Science

We strive for rigorous, reproducible research that advances fundamental knowledge while addressing real-world challenges.

Inclusive Community

We foster a diverse, supportive environment where all members can thrive and contribute their unique perspectives.

Collaborative Spirit

We actively collaborate with researchers worldwide, believing that the best science emerges from diverse partnerships.

Mentorship & Training

We are committed to training the next generation of scientists through hands-on research experience and professional development.

Our Impact

Scientific Contributions

  • RAD-seq Technology: Enabled genome-wide studies in thousands of non-model organisms
  • Stacks Software: Democratized population genomics analyses for the global research community
  • Evolutionary Insights: Advanced understanding of parallel evolution and adaptation

Education & Outreach

  • Trained over 50 undergraduate researchers
  • Mentored 25+ graduate students and 15+ postdocs
  • Engaged with K-12 students through outreach programs
  • Contributed to science communication and public understanding

Our Location

We are located in the Institute of Ecology and Evolution at the University of Oregon in Eugene, Oregon. Our facilities include:

  • State-of-the-art molecular biology laboratories
  • High-performance computing resources
  • Aquatic animal care facilities
  • Access to diverse field sites throughout Oregon

The University of Oregon provides an exceptional environment for evolutionary research, with strengths in: - Genomics and bioinformatics - Ecology and evolution - Data science - Environmental sciences

Funding & Support

Our research is generously supported by:

  • National Science Foundation (NSF)
  • National Institutes of Health (NIH)
  • Gordon and Betty Moore Foundation
  • M.J. Murdock Charitable Trust
  • University of Oregon

Contact Us

We welcome collaborations, inquiries about our research, and applications from prospective team members.

William A. Cresko, Ph.D.
Principal Investigator
wcresko@uoregon.edu

Laboratory Address:
Cresko Laboratory
Institute of Ecology and Evolution
312 Pacific Hall
University of Oregon
Eugene, OR 97403-5289

Phone: (541) 346-4779
Twitter: @creskolab
GitHub: github.com/wcresko