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New Publication: Rapid Evolution of Phenotypic Plasticity in C. remanei

news
publication
journal article
evolution
phenotypic plasticity
Author

Cresko Lab

Published

May 1, 2014

Exciting new publication in G3: Genes|Genomes|Genetics reveals rapid evolution of phenotypic plasticity in nematodes!

Dr. Kristin Sikkink, with co-authors Robert Reynolds, Kate Ituarte, Patrick Phillips, and Bill Cresko, demonstrates that apparent genetic assimilation can result from shifting thresholds of induction across environments. This groundbreaking work highlights the critical importance of environmental context for understanding evolution of phenotypic plasticity.

Major Findings

The research reveals: - Rapid evolution of plasticity thresholds - Variable genetic assimilation patterns across environments - Complex interactions between genes and environment - Evolution of heat shock protein responses - Hormetic effects under stress conditions

Research Innovation

This study pioneered: - Experimental evolution approaches in C. remanei - Multi-environment selection experiments - Analysis of shifting induction thresholds - Integration of stress biology and evolution - Novel frameworks for understanding plasticity

Evolutionary Significance

The work demonstrates: - Plasticity can evolve remarkably quickly - Environmental context shapes evolutionary trajectories - Genetic assimilation is more complex than previously thought - Natural selection acts on reaction norms - Stress responses are highly evolvable

Experimental Design

The research employed: - Multiple replicate selection lines - Controlled temperature stress regimes - Multi-generation experimental evolution - Comprehensive phenotypic measurements - Statistical analysis of evolutionary change

Broader Impacts

This research informs: - Climate change adaptation predictions - Understanding organismal stress responses - Evolution in variable environments - Conservation under changing conditions - Basic evolutionary theory

Collaborative Excellence

This publication represents: - Cross-institutional collaboration - Integration of multiple expertise areas - Graduate student leadership - Mentorship in experimental evolution - Team science success

Heat Shock Response

Key insights into: - Heat shock protein regulation - Stress response networks - Temperature adaptation mechanisms - Cellular protection strategies - Evolutionary constraints and opportunities

Read the paper →

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