Cresko Laboratory Cresko Laboratory
  • About
  • Team
  • Research
  • Funding
  • Publications
  • Press
  • News
  • Talks
  • Software
  • Teaching

New Publication: Computational Approaches for Mining Genomic Databases

news
publication
book chapter
bioinformatics
computational biology
Author

Cresko Lab

Published

January 27, 2014

We’re pleased to announce a new book chapter on computational approaches for mining publicly available genomic databases!

This comprehensive guide by Richard Voelker, William Cresko, and Clayton Burgland provides researchers with essential skills for efficiently obtaining, manipulating, and interrogating genomic data from public repositories. Published as part of a major bioinformatics methods collection, this chapter empowers scientists to leverage the wealth of publicly available genomic resources.

Chapter Highlights

The publication covers: - Introduction to primary genomic data repositories - Common file format specifications - Sequence annotation best practices - UCSC Genome Browser utilization - Genomic interval operations - BED format manipulation

Practical Application

A fully worked example demonstrates: - ChIP-seq data analysis - Annotation data integration - Query formulation strategies - Data visualization techniques - Result interpretation methods

Key Learning Objectives

Readers will master: - Efficient data retrieval from public databases - File format conversions and manipulations - Command-line tools for genomic analysis - Browser-based data exploration - Integration of diverse data types

Essential Skills

The chapter teaches: - Navigation of major genomic databases - Understanding of standardized file formats - Use of bedtools and related utilities - Custom track creation - Batch data processing

Target Audience

This resource benefits: - Graduate students entering genomics - Researchers new to bioinformatics - Biologists transitioning to computational work - Core facility personnel - Educators teaching genomics

Database Coverage

Featured repositories include: - NCBI/GenBank - UCSC Genome Browser - Ensembl - ENCODE project - Model organism databases

Computational Tools

Introduction to essential software: - Command-line utilities - Scripting approaches - Browser interfaces - Data manipulation tools - Visualization platforms

Educational Impact

This chapter serves as: - Laboratory training material - Course curriculum content - Self-study resource - Reference guide - Protocol foundation

Read the chapter →

© 2025 Cresko Laboratory

Built with Quarto

University of Oregon