RAD-seq for Genome Scans Highlighted in Science
The use of RAD sequencing for population genomic scans has been highlighted in Science!
This feature recognizes the transformative impact of RAD-seq technology on population genomics. The methodology, which our lab has helped pioneer, enables researchers to conduct genome-wide association studies and selection scans in organisms without reference genomes, democratizing genomics research across the tree of life.
About the Highlight
Science magazine features how RAD-seq is revolutionizing: - Population genomic studies in non-model organisms - Detection of signatures of natural selection - Genome-wide association studies (GWAS) - Understanding of local adaptation
Key Applications
The highlighted work demonstrates RAD-seq’s power for: - Identifying genomic regions under selection - Mapping traits in natural populations - Understanding population structure and gene flow - Conservation genomics applications
Methodological Innovation
RAD-seq enables researchers to: - Generate thousands of genetic markers economically - Study organisms without genomic resources - Conduct population-level sampling at genomic scales - Detect both neutral and adaptive genetic variation
Our Laboratory’s Contribution
The Cresko Lab has been at the forefront of developing RAD-seq applications for evolutionary genomics, contributing both methodological advances and empirical studies demonstrating its power.